ADR

Frequency

Serum creatinine

Baseline and at least monthly while receiving an injectable drug.

Serum potassium

At least monthly while receiving an injectable agent particularly those receiving capreomycin.

Thyroid stimulating hormone(TSH)

Baseline. Ideally, once between months 6 and 9 of treatment, if receiving ethionamide and/or PAS. Monitor for signs/symptoms of hypothyroidism.

Liver serum enzymes

Consider periodic monitoring in patients receiving pyrazinamide for extended periods of time or for patients at risk of hepatitis.